Figure 2. 12-metabolite index and relationship with memory performance.
This figure shows the derived 12-metabolite index for the three groups (SN, NC, and aMCI/AD) (a). Box-plot for index values between groups. Using multinomial logistic regression, the 12-metabolite index significantly differentiated the SN, NC, and aMCI/AD groups (all p < .013). The relationship between the 12-metabolite index and memory composite z-score is shown for each group of participants in the study (b). Zmem = Memory composite score; SN = Supernormal; NC = Normal control (combined NCs and NCo); aMCI/AD = amnestic mild cognitive impairment and Alzheimer’s disease. Note. ** p < .01; *** p < .001.