Table 1.
Genes that identify cells of the regenerative milieu.
| Cell Type | Markers | References |
|---|---|---|
| Muscle Stem Cells (MuSCs) | Pax7, Vcam1, SM/C2.6, α7-Integrin/CD34 | Fukada et al., 2004; Joe et al., 2010; Liu et al., 2015; Seale et al., 2000 |
| Fibroadipogenic Progenitors (FAPs) | Sca-1, PDGFRα, Tie-2 | Joe et al., 2010; Uezumi et al., 2010; Wosczyna et al., 2012 |
| M1 Macrophages | CD45, CD11b, CD68, Ly6c-high | Arnold et al., 2007; Villalta et al., 2009 |
| M2 Macrophages | CD45, CD11b, CD163, CD206 | Arnold et al., 2007; Villalta et al., 2009 |
| Eosinophils | CD45, CD11b, Siglec F | Heredia et al., 2013 |
| Regulatory T Cells (Tregs) | CD25, Fox3p, CD4 | Burzyn et al., 2013; Kuswanto et al., 2016 |
| Neutrophils | Ly6C, F4/80 negative | Tidball et al., 2010 |
| Vascular Endothelial Cells (ECs) | CD31, VwF, VE-Cadherin | Abou-Khalil et al., 2009; Christov et al., 2007; Wosczyna et al., 2012 |
| Pericytes | CD146, NG2, ALP, PDGFRβ | Dellavalle et al., 2007; Kostallari et al., 2015; Wosczyna et al., 2012; Zhu et al., 2008 |
| Fibroblasts | αSMA, ER-TR7, FSP-1, Tcf4 | Joe et al., 2010; Mathew et al., 2011; Uezumi et al., 2010 |