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. 2018 Dec 11;10:409. doi: 10.3389/fnagi.2018.00409

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Copyright © 2018 Westwood, Baird, Hye, Ashton, Nevado-Holgado, Anand, Liu, Newby, Bazenet, Kiddle, Ward, Newton, Desai, Tan Hehir, Zanette, Galimberti, Parnetti, Lleó, Baker, Narayan, van der Flier, Scheltens, Teunissen, Visser and Lovestone.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Schematic diagram illustrating the experimental work flow of the present study for the discovery, replication, and validation of plasma proteins associated with brain pathology. AD, Alzheimer’s disease; MCI, mild cognitive impairment; SCD, subjective cognitive decline; CSF, cerebrospinal fluid; TMT, tandem mass tagging; LC-MS/MS, liquid chromatography tandem mass spectrometry; Aβ, amyloid-beta.