Table 1. Discovery sample description.
| Ethnic Group | Cohort | N | Age | Percent Female | BMI | Sleep Episode SpO2 | Minimum Sleep Episode SpO2 | Percent Sleep Under 90% SpO2 | Apnea Hypopnea Index | AHI (% <5, 5–15, > = 15) | Waking SpO2 | FVC (% Predicted) | % Asthma | COPD | % Diabetes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| African-American | CFS* | 719 | 37.8 (19.4) | 55.6 | 31.6 (9.6) | 94.57 (3.77) | 85.82 (9.88) | 4.58 (13.14) | 5.61 (19.68) | 47.1, 21.2, 31.7 | 97.78 (1.91) | 95.10 (19.67) | 21.5 | 15.9 | 15.8 |
| MESA | 490 | 69.1 (9.1) | 54.3 | 30.4 (5.7) | 94.44 (1.96) | 82.93 (8.17) | 4.01 (9.46) | 13.34 (21.16) | 21.2, 32.2, 46.5 | 96.11 (1.35) | 96.02 (17.62) | 5.3 | 14.1 | 28.0 | |
| Asian-American | MESA | 228 | 68.1 (9.2) | 50.4 | 24.1 (3.2) | 94.96 (1.22) | 83.42 (7.38) | 2.17 (4.30) | 13.97 (23.90) | 22.4, 30.3, 47.4 | 96.18 (1.01) | 98.45 (15.49) | 4.4 | 16.6 | 16.0 |
| European-American | ARIC | 1,432 | 62.4 (5.7) | 51.5 | 28.8 (5.1) | 94.47 (1.99) | 85.62 (6.12) | 3.36 (10.33) | 8.67 (15.55) | 3.0, 34.5, 32.5 | 96.08 (1.70) | 102.39 (13.48) | 7.3 | 0.9 | 6.1 |
| CFS* | 692 | 41.6 (19.5) | 52.8 | 30.2 (8.7) | 93.74 (3.67) | 86.46 (9.07) | 4.29 (12.30) | 5.52 (18.17) | 48.6, 20.7, 30.8 | 96.96 (2.01) | 95.68 (18.05) | 15.4 | 18.6 | 9.2 | |
| FHS* | 640 | 59.4 (9.0) | 50.0 | 28.5 (5.0) | 94.68 (1.96) | 85.71 (6.07) | 2.79 (8.16) | 8.20 (14.42) | 34.5, 35.5, 30.0 | 96.15 (1.86) | 101.45 (13.41) | 7.7 | 0.4 | 5.3 | |
| MESA | 707 | 68.5 (9.1) | 53.6 | 28.0 (5.2) | 93.93 (1.75) | 83.49 (7.41) | 4.36 (10.84) | 12.62 (20.67) | 21.6, 34.4, 44.0 | 95.70 (1.40) | 94.43 (14.08) | 2.0 | 13.6 | 11.1 | |
| MrOS | 2,178 | 76.7 (5.7) | 0.0 | 27.2 (3.7) | 93.85 (1.73) | 84.30 (6.08) | 4.41 (9.89) | 12.74 (18.13) | 21.2, 35.0, 43.8 | 94.96 (1.63) | 98.99 (18.33) | 7.5 | 5.3 | 13.0 | |
| Hispanic/ Latino-American | MESA | 458 | 68.3 (9.2) | 52.8 | 30.1 (5.5) | 94.33 (1.56) | 81.50 (9.38) | 3.84 (7.35) | 16.94 (23.05) | 17.2, 27.9, 54.8 | 96.12 (1.37) | 94.42 (14.91) | 5.5 | 9.2 | 27.6 |
| Starr | 782 | 52.3 (11.3) | 71.9 | 32.2 (6.8) | 94.65 (2.09) | 85.78 (7.50) | 2.83 (8.79) | 10.35 (17.18) | 31.5, 31.5, 37.1 | 95.93 (2.43) | N/A | N/A | N/A | 47.90 |
Six studies included 8,326 individuals with genotypes and phenotypes (1,209 African-Americans; 228 Asian-Americans; 5,649 European-Americans; 1,240 Hispanic/Latino-Americans). Values are displayed as mean (SD), except for the skewed Apnea Hypopnea Index, which is displayed as median (IQR). Waking O2 saturation values were based on point measurements collected prior to the sleep episode.
*: Family cohort.