Table 1.
Postnatal distribution of m-Msi-1 in the CNS
| Region | P3–P7 | Adult | |
|---|---|---|---|
| SVZ and ventricular zone (lateral, third and fourth ventricles) | +++ | +++ | SVZ cells (subependymal cells) Ependymal cells |
| White matter tracts | |||
| Corpus callosum | ++ | ++ | Astrocytes |
| Cerebellar folia white matter | ++ | + | Astrocytes |
| Cerebral cortex | |||
| Layer I | + | ++ | Astrocytes (fibrous?) |
| Layers II–VI | + | ++ | Astrocytes (protoplasmic?) |
| Hippocampus | |||
| CA1 | − | − | |
| CA2 | − | − | |
| CA3 | − | − | |
| Dentate gyrus | + | + | Astrocytes (subgranular layer) |
| Hilus | + | + | Astrocytes |
| Stratum radiatum | + | + | Astrocytes |
| Basal nuclei | |||
| Caudate-putamen | ++ | + | Astrocytes |
| Globus pallidus | ++ | + | Astrocytes |
| Colliculi | |||
| Inferior | + | + | Astrocytes |
| Superior | + | + | Astrocytes |
| Cerebellum | |||
| External granular cell layer | ++ | − | |
| Molecular layer | ++ | + | Stellate cells |
| Purkinje cell layer | ++ | + | Bergmann glia |
| Internal granular cell layer | + | + | Astrocytes |
The immunoreactivities are assessed as intense, +++; moderate, ++; weak, +; or not detectable, −.