Table 2.
Scrublet-Predicted and Experimentally Expected Doublet Fractions
| Dataset | Scrublet outputs | Experimental rate | ||||
|---|---|---|---|---|---|---|
| Detected doublets (δ) | Detectable doublet fraction (ϕD) | Overall doublet rate (δ/ϕD) | Overall doublet rate () | Rationale | ||
| Mouse-human (Figure 3) | 5.9% | 54% | 10.9% | ↔ | 11.6% | Using mouse versus human genomes |
| Demuxlet (Figure 4) | 8.1% | 55% | 14.6% | ↔ | 12.2% | Using human SNPs |
| PBMCs (Figure 5B) | 1.8% | 53% | 3.5% | ↔ | 3% | Nominal doublet rate |
| PBMCs (Figure 5C) | 4.1% | 61% | 6.8% | ↔ | 6% | Nominal doublet rate |
| Bone marrow (Figure 6) | 3.6% | 43% | 8.3% | ↔ | 5%–10% | inDrops observed droplet occupancy |