Figure 3. CD38-/- adult male mice display aggressive behaviour in a social interaction task.
(A) Left panel shows the analysis of the proportion of mice emitting USVs in the C57BL/6 (n=14 mice), and CD38-/- groups (n=10 mice). White sections represent the proportion of vocalizing mice and grey section represent the proportion of non-vocalizing mice. Central histogram shows the time spent in social contact between tested mice (C57BL/6, n=14 mice; CD38-/-, n=10 mice) and visitors in an 8 min-session. Right histogram shows the number of bites recorded during the session for C57BL/6 mice (n=14) and CD38-/- mice (n=10). (B) Left panel shows the proportion of juvenile mice emitting USVs (C57BL/6, n=9 mice; CD38-/-, n=9 mice). Right histogram shows the time spent in social contact between host juvenile tested mice (C57BL/6, n=19 mice; CD38-/-, n=13 mice) and juvenile visitors in a session of 8 min. (C). Left panel shows a drawing of the three-chamber test apparatus. The histogram in the centre shows the number of social and non-social contacts made by C57BL/6 adult mice and CD38-/- adult mice. Right histogram shows contact duration during social and non-social contacts in C57BL/6 mice and CD38-/- (C57BL/6, n=15 mice; CD38-/-, n=10 mice). Error bars represent S.E.M., Mann-Whitney, two-tailed (*p<0.05; **p < 0.01).