Figure 2.
The sAHP is enlarged in CA1 neurons of AI rats. A, Representative waveforms (average, n = 5 sweeps) taken from a young (Y), an AU, and an AI rat. In each case, the sAHP was evoked with a 50 ms current pulse sufficient to trigger four action potentials. The Vm was held at -50 mV by tonic current injection. B, Summary of sAHP amplitudes from all cells recorded from either resting or depolarized potentials using a constant or pulsed current injection protocol to elicit action potentials. #p < 0.001 compared with the AU or young groups (Y, n = 32; AU, n = 40; AI, n = 30). C, Distribution of sAHP amplitudes from all cells examined recorded from 50 mV using a 50 ms square wave current pulse to elicit action potentials.