Table 1.
Characteristics of subjects
|
|
Control subjects |
Schizophrenic subjects |
||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pair
|
Case
|
Sex/race
|
Age
|
PMI a
|
Brain pH
|
Storage time b
|
Cause of death c
|
Case
|
DSM IV diagnosis
|
Sex/race
|
Age
|
PMI a
|
Brain pH
|
Storage time b
|
Cause of death c
|
|||||||||||||
| 1 | 592 | M/B | 41 | 22.1 | 6.72 | 59 | ASCVD | 533 | Chronic undifferentiated schizophrenia | M/W | 40 | 29.1 | 6.82 | 69 | Accidental asphyxiation | |||||||||||||
| 2 | 567 | F/W | 46 | 15.0 | 6.72 | 63 | Mitral valve prolapse | 537 | Schizoaffective disorder k | F/W | 37 | 14.5 | 6.68 | 68 | Suicide by hanging | |||||||||||||
| 3 | 516 | M/B | 20 | 14.0 | 6.86 | 70 | Homicide by gun shot | 547 | Schizoaffective disorder | M/B | 27 | 16.5 | 6.95 | 66 | Heat stroke | |||||||||||||
| 4 | 630 | M/W | 65 | 21.2 | 6.95 | 53 | ASCVD | 566 | Chronic undifferentiated schizophrenia d | M/W | 63 | 18.3 | 6.80 | 63 | ASCVD | |||||||||||||
| 5 | 604 | M/W | 39 | 19.3 | 7.08 | 56 | Hypoplastic coronary artery | 581 | Chronic paranoid schizophrenia ef | M/W | 46 | 28.1 | 7.22 | 61 | Accidental combined drug overdose | |||||||||||||
| 6 | 546 | F/W | 37 | 23.5 | 6.74 | 67 | ASCVD | 587 | Chronic undifferentiated schizophrenia d | F/B | 38 | 17.8 | 7.02 | 60 | Myocardial hypertrophy | |||||||||||||
| 7 | 558 g | M/W | 47 | 6.6 | 6.99 | 64 | ASCVD | 317 | Chronic undifferentiated schizophrenia | M/W | 48 | 8.3 | 6.07 | 115 | Pneumonia | |||||||||||||
| 8 | 635 h | F/W | 54 | 17.8 | 6.47 | 52 | ASCVD | 597 | Schizoaffective disorder | F/W | 46 | 10.1 | 7.02 | 58 | Pneumonia | |||||||||||||
| 9 | 551 | M/W | 61 | 16.4 | 6.63 | 66 | Cardiac tamponade | 625 | Chronic disorganized schizophrenia g | M/B | 49 | 23.5 | 7.32 | 54 | ASCVD | |||||||||||||
| 10 | 685 | M/W | 56 | 14.5 | 6.57 | 46 | Hypoplastic coronary artery | 622 | Chronic undifferentiated schizophrenia k | M/W | 58 | 18.9 | 6.78 | 54 | Right MCA infarction | |||||||||||||
| 11 | 681 | M/W | 51 | 11.6 | 7.15 | 46 | Hypertrophic cardiomyopathy | 640 | Chronic paranoid schizophrenia | M/W | 49 | 5.2 | 6.86 | 52 | Pulmonary embolism | |||||||||||||
| 12 | 806 | M/W | 57 | 24.0 | 6.94 | 25 | Pulmonary thrombo-embolism | 665 | Chronic paranoid schizophrenia e | M/B | 59 | 28.1 | 6.92 | 49 | Intestinal hemorrhage | |||||||||||||
| 13 | 822 | M/B | 28 | 25.3 | 7.04 | 22 | ASCVD | 787 | Schizoaffective disorder i | M/B | 27 | 19.2 | 6.67 | 29 | Suicide by gun shot | |||||||||||||
| 14 | 727 | M/B | 19 | 7.0 | 7.15 | 39 | Trauma | 829 | Schizoaffective disorder ejk | M/W | 25 | 5.0 | 6.80 | 20 | Suicide by drug overdose | |||||||||||||
| 15
|
871
|
M/W
|
28
|
16.5
|
7.14
|
12
|
Trauma
|
878
|
Disorganized schizophrenia e
|
M/W
|
33
|
10.8
|
6.72
|
11
|
Myocardial fibrosis
|
|||||||||||||
| Mean | 43.3 | 17.0 | 6.88 | 49.3 | 43.0 | 16.9 | 6.84 | 52.3 | ||||||||||||||||||||
|
|
SD
|
|
14.6
|
5.8
|
0.22
|
17.8
|
|
|
|
|
12.0
|
8.0
|
0.28
|
24.1
|
|
|||||||||||||
a
PMI indicates postmortem interval in hours
b
storage time (months) at −80°C
c
ASCVD indicates atherosclerotic coronary vascular disease
d
alcohol abuse, in remission at time of death
e
alcohol dependence, current at time of death
f
other substance abuse, current at time of death
g
alcohol abuse, current at time of death
h
depressive disorder
i
other substance dependence, current at time of death
j
other substance abuse, in remission at time of death
k
schizophrenic subjects off medications at time of death.