Table 1.
Passive properties of PCs
| Wild-type (n = 9) | GluRδ2 mutant (n = 11) | |
|---|---|---|
| C1 (pF) | 73.8 ± 12.9 | 67.2 ± 20.3 |
| C2 (pF) | 684 ± 1011-160 | 513 ± 75.21-160 |
| R1 (MΩ) | 9.3 ± 1.3 | 7.9 ± 2.4 |
| R2 (MΩ) | 10.6 ± 2.7* | 14.9 ± 4.6* |
| R3 (MΩ) | 145.7 ± 41.51-160 | 212.8 ± 47.11-160 |
Parameters were calculated on the basis of the model described byLlano et al. (1991), which distinguishes two regions of PCs: region 1 representing the soma and the main proximal dendrites, and region 2 representing the dendritic tree. C1 represents the lumped membrane capacitance of region 1, and R1 represents the pipette access resistance. Region 2 is linked to region 1 by resister R2, which represents the lumped resistance between the main proximal dendrite and each membrane region of the distal dendrites. C2 and R3 represent the lumped capacitance and resistance, respectively, of the dendritic tree of PCs. Data are expressed as mean ± SD.
F1-160: p < 0.01;
*
p < 0.05 (two-tailed t test).