Fig. 5.
Mediation of anion channel-induced [Ca2+]i increases by voltage-activated Ca2+ channels. A, The [Ca2+]i transient caused by bath-applied GABA (200 μm) is suppressed in nominally Ca2+-free superfusate. B, Ca2+-free saline also abolishes the [Ca2+]i rise in response to glycine (1 mm). C, The Ca2+ channel antagonist nifedipine (50 μm) reduces the glycine-evoked [Ca2+]i response. D, Statistical analysis of the blocking effects of Ca2+-free saline and nifedipine on agonist-induced [Ca2+]i rises.