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mRNA induction correlates with Aβ aggregation and Aβ neurotoxicity. Changes in neuronal viability and Aβ aggregation (A) and gene expression (B, C) were assessed in neurons treated with Aβ1–40(40 μm, lot ZM605) solvated initially in either water or DMSO. Values for the alamarBlue and ThT assays are expressed as mean ± SD (error bars) from triplicate wells. Similar results were observed in at least two independent neuronal culture preparations.
