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. Author manuscript; available in PMC: 2019 Nov 12.
Published in final edited form as: Clin Oncol (R Coll Radiol). 2019 Apr 19;31(7):407–415. doi: 10.1016/j.clon.2019.04.001

Fig 2.

Fig 2.

Chronology of physical, physicochemical, chemical, biochemical and biological events occuring after irradiation in the biological tissue. The difference between FLASH radiotherapy and radiotherapy delivered at the conventional dose rate is the duration of the exposure to the ionising radiation during the chemical step of the cascade. The chemical steps are highly dependent on dioxygen concentration within tissues.