Table 3.
Predictors of increased mortality without emergent transplant: King’s College Criteria [67]
| Acetaminophen-induced ALF | Non-acetaminophen-induced ALF |
|---|---|
| Arterial pH < 7.30 | Prothrombin time greater than 100 s (INR > 6.5) |
| OR | OR 3 OF THE 5 FOLLOWING: |
| Grade 3 or 4 encephalopathy AND | Patient age <10 or >40 years |
| Serum creatinine >300 mcg/ml (3.4 mg/dl) AND | Hepatitis due to non-A/non-B virus, halothane, or drug reaction |
| Prothrombin time greater than 100 s (INR > 6.5) |
Delayed onset of encephalopathy (>1 week after onset of jaundice) Serum total bilirubin >18 mg/dl (308 mmol/l) PT greater than 50 s (INR > 3.5) |