Table 1.
The genes predicted by GeneMark.hmm for the SARS-CoV, TOR2 strain
Gene | Start | Stop | Gene length (bp) |
1 | <3 | 53 | 51 |
2 | 265 | 13,413 | 13,149 |
3 | 13,599 | 21,485 | 7887 |
4 | 21,492 | 25,259 | 3768 |
5 | 25,268 | 26,092 | 825 |
6 | 26,398 | 27,063 | 666 |
7 | 27,074 | 27,265 | 192 |
8 | 27,273 | 27,641 | 369 |
9* | 27,864 | 28,118 | 255 |
10* | 28,130 | 28,426 | 297 |
11* | 28,423 | 29,388 | 966 |
The same genome was submitted several times to the website, however, the prediction results were not identical at all times, indicating that the system is unstable. An important structural protein gene (N protein), which is located from 28120 to 29388, was predicted as ‘gene 10’ and ‘gene 11’ in some predicted results. Sometimes, ‘gene 9,’ a quite conserved ORF in all of the 11 SARS-CoV genomes mentioned above, was not predicted. In addition, the gene coding for a structural protein (small envelope protein E) was also missed by the prediction. For more details, see the text.