Table 2.
Latifolians A and B as a new class of natural product JNK inhibitors
Inhibitor | Inhibitor Structure | Identification | IC50 | PDB entry | Reference |
---|---|---|---|---|---|
Latifolian A | ![]() |
High throughput screening of 100,000 natural extracts for inhibitors of JNK3 activity in vitro. | IC50 JNK3 = 13 μM | – | [71] |
Latifolian B | ![]() |
High throughput screening of 100,000 natural extracts for inhibitors of JNK3 activity in vitro. | IC50 JNK3 = 10 μM | – | [71] |