Figure 1. Positron Emission Tomography With [18F]flortaucipir Visual Read Categories and Comparative Histologic Structure.
Three cases representing the 3 levels of visual reads and corresponding histologic sections from the superior or middle temporal (sup/middle temp) gyrus (Braak region of interest [ROI] 7) and middle frontal gyrus (Braak ROI 6) stained for neurofibrillary tangles (NFTs) with AT8 antibodies and for amyloid plaque with 6E10 antibodies. Images presented in a blue-green-red-yellow color scale, with cortical counts scaled to 1.65 × the mean cerebellar counts (eAppendix in the Supplement). A indicates anterior; AD, Alzheimer disease; L, left; P, posterior; R, right.