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Oxford University Press - PMC COVID-19 Collection logoLink to Oxford University Press - PMC COVID-19 Collection
. 2020 Apr 27:ciaa489. doi: 10.1093/cid/ciaa489

Profile of IgG and IgM antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Jiuxin Qu 1,2,, Chi Wu 1,2, Xiaoyong Li 1, Guobin Zhang 1, Zhaofang Jiang 1, Xiaohe Li 2, Qing zhu 1, Lei Liu 3,2
PMCID: PMC7197626  PMID: 32337590

Abstract

We profiled the serological responses to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) nucleocapsid (N) protein and spike (S) glycoprotein. The majority of the patients developed robust antibody responses between 17 and 23 days after illness onset. Delayed, but stronger antibody responses were observed in critical patients.

Keywords: SARS-CoV-2, COVID-19, Serologic Responses, IgG, IgM


Articles from Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America are provided here courtesy of Oxford University Press

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