. 2012 May 23;142(7):1266–1271. doi: 10.3945/jn.111.150995

TABLE 1.

Denuded villi surface area, initial PGE₂ concentration, andCOX-2 mRNA expression in control and ischemic ileum of piglets fed 0, 0.5, or 5% ARA or 5% EPA¹

	0% ARA		0.5% ARA		5% ARA		5% EPA		Pooled SEM	P value
	Nonischemic	Ischemic	Nonischemic	Ischemic	Nonischemic	Ischemic	Nonischemic	Ischemic		Diet	Treatment	Diet × treatment
Denuded villi surface area,%	6.9^c	62.8^a	7.7^c	65.5^a	6.9^c	43.6^b	4.7^c	60.0^a	3.6	0.13	<0.001	0.001
Initial PGE_2,²ng/L	140^b	124^b	142^b	101^bc	200^b	317^a	33^c	21^c	45	<0.001	0.31	0.27
COX-2 mRNA,³relative expression ratio	0.78^b	1.44^b	1.00^b	1.30^b	1.11^b	1.14^b	3.68^a	2.81^a	0.47	<0.001	0.93	0.43

Values are mean ± SEM, = 6. Means in a row without a common letter differ,P ≤ 0.05. ARA, arachidonic acid; COX, cyclooxygenase.

Measured after 30 min on Ussing chamber.

Normalized relative to nonischemic, 0.5% ARA treatment.