Li 2005.
| Methods | RCT design: Parallel‐group trial Total N randomised: 87 Length of follow‐up: 6 weeks Analysis: unclear (2 cases lost in the treatment group, 3 cases lost in the control group) |
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| Participants | Location: China Number of study centres and setting: Hospitalized patients (number of centres unclear) CAD diagnosis: Patients after Coronary Artery Bypass Grafting (CABG) Depression diagnosis: Self‐rated Hamilton Depression Rating Scale (HAM‐D) score >18 Other entry criteria: unclear Exclusion criteria: unclear Treatment N: 43 (sex and age distribution unclear) Control N: 39 (sex and age distribution unclear) Comparability of groups: unclear |
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| Interventions | Treatment: St. John's Wort extract (300 mg, 3 times a day) Control: Placebo Duration of treatment: 6 weeks |
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| Outcomes | Review outcomes: HAM‐D score Other outcomes: Ventricular function (Tei‐Index), side‐effects |
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| Funding | unclear | |
| Notes | ||
| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Random sequence generation (selection bias) | Unclear risk | not applicable |
| Allocation concealment (selection bias) | Unclear risk | not applicable |
| Blinding (performance bias and detection bias) All outcomes | Unclear risk | not applicable |
| Incomplete outcome data (attrition bias) All outcomes | Unclear risk | not applicable |
| Selective reporting (reporting bias) | Unclear risk | not applicable |
| Other bias | Unclear risk | not applicable |