UPBEAT 2007.
| Trial name or title | Understanding prognostic benefits of exercise and antidepressant therapy (UPBEAT) NCT00302068 |
| Methods | RCT design: 3‐armed parallel‐group trial Target number of participants: 200 Length of follow‐up: 12 months |
| Participants | Location: USA Inclusion criteria: Patients with coronary heart disease (CHD) and depressive symptoms (Beck Depression Inventory (BDI‐II) score 9 or greater) |
| Interventions | Treatment: Aerobic exercise Active comparator: Sertraline Control: Placebo |
| Outcomes | Primary outcome: Hamilton Rating Scale for Depression (HAM‐D) |
| Starting date | July 2006 |
| Contact information | James A. Blumenthal, PhD: blume003@mc.duke.edu Andrew Sherwood, PhD: sherw002@mc.duke.edu |
| Notes | Funding: National Heart, Lung, and Blood Institute, USA |