Fig. 6.
Increased frequency of IL-17A-producing γδ T cells in children with newly diagnosed type 1 diabetes (T1D). Frequencies of γδ T cells (a), iNKT cells (b) and NK cells (c) in control, AAb+ and T1D groups. Linear regression lines for log10-transformed γδ T cell (d), iNKT cell (e) and NK cell (f) frequencies vs log10-transformed MAIT cell frequencies were calculated for the control, AAb+ and T1D groups. The slopes and elevations of the regression lines were not statistically different between the groups. Correlation was calculated by pooling all samples analysed and is expressed together with p values on the individual plots. Frequencies of IL-17A-producing γδ T cells (g) and iNKT cells (h) in control, AAb+ and T1D groups. Median values with IQRs are shown; plotted on a log10 scale in (b).**p < 0.01; Kruskal–Wallis test with Dunn’s post hoc test