Table 1.
Meta-regression of moderators of the gait parameters of Parkinson’s disease.
Outcome/moderator | Number of study estimates | β | 95% CI | p value | R2 |
---|---|---|---|---|---|
Speed | |||||
Age | 26 | 0.053 | 0.033 to 0.140 | 0.227 | 0.01 |
H&Y | 26 | 0.124 | 0.546 to 0.814 | 0.722 | − 0.04 |
UPDRS | 26 | 0.013 | 0.045 to 0.018 | 0.414 | − 0.05 |
Disease duration | 26 | 0.020 | 0.131 to 0.173 | 0.789 | − 0.05 |
Stride length | |||||
Age | 21 | − 0.001 | − 0.080 to 0.080 | 0.997 | − 0.11 |
H&Y | 21 | − 0.586 | − 1.283 to 0.110 | 0.098 | 0.15 |
UPDRS | 21 | − 0.022 | − 0.061 to 0.015 | 0.244 | 0.00 |
Disease duration | 21 | 0.003 | − 0.146 to 0.152 | 0.960 | − 0.10 |
Cadence | |||||
Age | 16 | 0.041 | 0.137 to 0.055 | 0.400 | − 0.05 |
H&Y | 16 | 0.558 | 0.191 to 0.075 | 0.084 | 0.23 |
UPDRS | 16 | 0.003 | 0.026 to 0.032 | 0.840 | − 0.08 |
Disease duration | 16 | 0.061 | 0.124 to 0.247 | 0.515 | − 0.05 |
Step width | |||||
Age | 7 | 0.230 | 0.121 to 0.469 | 0.058 | 0.37 |
H&Y | 7 | 0.371 | 0.779 to 1.522 | 0.526 | − 0.54 |
UPDRS | 7 | 0.005 | 0.264 to 0.253 | 0.967 | − 0.31 |
Disease duration | 7 | 0.106 | 0.233 to 0.447 | 0.539 | − 0.29 |
Double support | |||||
Age | 7 | 0.001 | 0.183 to 0.179 | 0.986 | − 0.32 |
H&Y | 7 | 0.170 | 0.469 to 1.811 | 0.838 | − 0.31 |
UPDRS | 7 | 0.006 | 0.107 to 0.120 | 0.913 | − 0.31 |
Disease duration | 7 | 0.026 | 0.053 to 0.001 | 0.058 | 0.49 |
Single support | |||||
Age | 4 | 0.163 | 0.836 to 0.509 | 0.633 | − 0.40 |
H&Y | 4 | 0.940 | 2.887 to 4.768 | 0.630 | − 0.37 |
UPDRS | 4 | 0.020 | 0.173 to 0.132 | 0.794 | − 0.46 |
Disease duration | 4 | 0.134 | 0.340 to 0.609 | 0.579 | − 0.40 |
Swing time | |||||
Age | 11 | 0.069 | 0.226 to 0.086 | 0.381 | − 0.12 |
H&Y | 4 | 2.535 | 0.083 to 4.987 | 0.042 | 0.57 |
UPDRS | 6 | 0.149 | 0.246 to 0.052 | 0.002 | 0.67 |
Disease duration | 5 | 0.177 | 0.115 to 0.469 | 0.234 | 0.06 |
p-values in bold indicate statistical significance (p < 0.05).
H&Y Hoehn and Yahr scale, UPDRS unified Parkinson's disease rating scale.