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. 2021 Jan 12;11:752. doi: 10.1038/s41598-020-80768-2

Table 1.

Meta-regression of moderators of the gait parameters of Parkinson’s disease.

Outcome/moderator Number of study estimates β 95% CI p value R2
Speed
Age 26 0.053 0.033 to 0.140 0.227 0.01
H&Y 26 0.124 0.546 to 0.814 0.722 − 0.04
UPDRS 26 0.013 0.045 to 0.018 0.414 − 0.05
Disease duration 26 0.020 0.131 to 0.173 0.789 − 0.05
Stride length
Age 21 − 0.001 − 0.080 to 0.080 0.997 − 0.11
H&Y 21 − 0.586 − 1.283 to 0.110 0.098 0.15
UPDRS 21 − 0.022 − 0.061 to 0.015 0.244 0.00
Disease duration 21 0.003 − 0.146 to 0.152 0.960 − 0.10
Cadence
Age 16 0.041 0.137 to 0.055 0.400 − 0.05
H&Y 16 0.558 0.191 to 0.075 0.084 0.23
UPDRS 16 0.003 0.026 to 0.032 0.840 − 0.08
Disease duration 16 0.061 0.124 to 0.247 0.515 − 0.05
Step width
Age 7 0.230 0.121 to 0.469 0.058 0.37
H&Y 7 0.371 0.779 to 1.522 0.526 − 0.54
UPDRS 7 0.005 0.264 to 0.253 0.967 − 0.31
Disease duration 7 0.106 0.233 to 0.447 0.539 − 0.29
Double support
Age 7 0.001 0.183 to 0.179 0.986 − 0.32
H&Y 7 0.170 0.469 to 1.811 0.838 − 0.31
UPDRS 7 0.006 0.107 to 0.120 0.913 − 0.31
Disease duration 7 0.026 0.053 to 0.001 0.058 0.49
Single support
Age 4 0.163 0.836 to 0.509 0.633 − 0.40
H&Y 4 0.940 2.887 to 4.768 0.630 − 0.37
UPDRS 4 0.020 0.173 to 0.132 0.794 − 0.46
Disease duration 4 0.134 0.340 to 0.609 0.579 − 0.40
Swing time
Age 11 0.069 0.226 to 0.086 0.381 − 0.12
H&Y 4 2.535 0.083 to 4.987 0.042 0.57
UPDRS 6 0.149 0.246 to 0.052 0.002 0.67
Disease duration 5 0.177 0.115 to 0.469 0.234 0.06

p-values in bold indicate statistical significance (p < 0.05).

H&Y Hoehn and Yahr scale, UPDRS unified Parkinson's disease rating scale.