Table 1.
Demographic and clinical characteristics of patients. All data are presented as mean (SD) or median (inter-quartile range).
| PD n = 13 |
MSA n = 9 |
PSP n = 13 |
CBD n = 9 |
AD n = 51 |
FTD n = 26 |
VD n = 14 |
p-Value | |
|---|---|---|---|---|---|---|---|---|
| Sex (m/f) | 8/5 | 6/3 | 9/4 | 4/5 | 18/33 | 15/11 | 9/5 | 0.132 † |
| Age | 57.5 (11.1) |
61.4 (9.3) |
60.8 (5.2) |
68.9 (8.0) |
66.5 (11.0) | 59.6 (8.7) |
71.1 (10.9) |
0.001 * |
| Disease duration (y) | 7.0 (4.0–8.0) |
3.0 (1.5–3.0) |
3.0 (1.5–3.0) |
2.0 (2.0–2.5) |
3.0 (2.0–5.0) |
3.0 (2.0–5.0) |
3.0 (2.0–3.0) |
0.010 ‡ |
| UPDRS | 24.5 (16.5) |
15.4 (17.9) |
20.5 (11.4) |
26.0 (8.7) |
NA | NA | NA | 0.442 * |
| MMSE | 28 (26–29) |
29 (26–29.5) |
24 (22.5–28.5) |
24 (19.5–28) |
19 (13–23) |
24 (17–27) |
22 (20–24) |
<0.0001 ‡ |
| Clox 2 test | 13 (10–13) |
13 (12–14.5) |
9.5 (8.0–10.0) |
8 (2–10) |
10 (5–12) |
12 (8–14) |
8 (7–12) |
0.002 ‡ |
| FAB | 14.5 (10–16) |
14.5 (12.5–16.5) |
11 (10–14) |
9.5 (6.5–12.5) |
10 (7–13) |
11 (3–12) |
11 (6–12) |
0.055 ‡ |
| 5-word delayed recall test | 5 (5–5) |
5 (5–5) |
5 (4–5) |
4 (3–5) |
1.5 (1–3) |
4.5 (0–5) |
5 (4–5) |
0.003 ‡ |
UPDRS: Unified Parkinson’s Disease Rating Scale; MMSE: Mini Mental State Examination; Clox 2 test: 15-point clock drawing test; FAB: Frontal Assessment Battery; †: x2 test; *: analysis of covariance, with sex, age and disease duration as covariates; ‡: independent samples Kruskal–Wallis test.