Table 2.
PrPSc glycotype analyses (in %) by participating laboratories. Values refer to the relative % of unglycosylated (upper), monoglycosylated (middle), and unglycosylated (lower) PrPSc isoforms based on densitometric analyses.
| Lab | RV1 | RV4 | RV5 | RV6 | RV8 | RV12 | RV13 | RV14 | RV16 | RV17 | RV18 | RV19 | RV20 | RV21 | RV22 | RV23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 17.5 | 26.5 | 25.4 | 14.7 | 23.2 | 13.2 | 14.4 | 29.7 | 20.8 | 20.2 | 10.2 | 14.0 | 15.6 | 59.6 | 60.9 | 16.2 |
| 47.1 | 47.6 | 43.8 | 37.0 | 42.1 | 45.2 | 44.2 | 37.8 | 42.3 | 35.2 | 45.4 | 44.3 | 41.1 | 23.7 | 24.9 | 33.3 | |
| 35.4 | 25.9 | 30.8 | 26.3 | 34.7 | 41.6 | 41.4 | 32.5 | 36.9 | 44.6 | 44.4 | 41.7 | 43.3 | 16.7 | 14.2 | 50.5 | |
| 2 | 33.4 | 37.6 | 36.8 | 29.0 | 25.9 | 29.6 | 38.6 | 39.8 | 35.5 | 33.4 | 19.8 | 27.2 | 33.7 | 57.5 | 59.4 | 33.3 |
| 43.1 | 44.0 | 43.3 | 45.2 | 42.7 | 44.4 | 43.5 | 42.8 | 40.6 | 46.2 | 49.5 | 44.9 | 42.4 | 30.3 | 31.3 | 37.9 | |
| 23.5 | 18.4 | 19.9 | 25.8 | 31.4 | 26.0 | 17.9 | 17.4 | 23.9 | 20.4 | 30.7 | 27.9 | 23.9 | 12.2 | 9.3 | 28.8 | |
| 3 | 15.3 | 30.9 | 25.9 | 17.6 | 21.3 | 20.1 | 35.0 | 27.4 | 27.7 | 19.0 | 16.9 | 25.1 | 17.7 | 52.5 | 51.8 | 24.3 |
| 46.5 | 40.1 | 33.0 | 47.3 | 40.7 | 38.5 | 39.5 | 36.6 | 40.8 | 41.0 | 45.5 | 36.7 | 34.5 | 24.1 | 26.9 | 33.6 | |
| 38.2 | 29.0 | 41.1 | 35.1 | 38.0 | 41.4 | 25.5 | 36.0 | 31.5 | 40.0 | 37.6 | 38.2 | 47.8 | 23.4 | 12.3 | 42.1 | |
| 4 | 20.4 | 25.6 | 26.0 | 25.3 | 21.1 | 24.8 | 30.9 | 29.3 | 33.9 | 18.5 | 10.0 | 23.7 | 32.5 | 48.8 | 47.2 | 19.9 |
| 44.0 | 48.5 | 43.9 | 37.8 | 44.6 | 43.4 | 40.8 | 38.2 | 43.4 | 48.6 | 47.1 | 46.8 | 41.8 | 32.9 | 34.2 | 43.4 | |
| 35.6 | 25.9 | 30.1 | 36.9 | 34.3 | 31.8 | 28.3 | 32.5 | 22.7 | 32.9 | 42.9 | 29.5 | 25.7 | 18.3 | 18.6 | 36.7 | |
| 5 | 29.5 | 31.1 | 30.5 | 33.1 | 32.1 | 45.9 | 39.5 | 36.9 | 35.6 | 17.1 | 24.3 | 36.5 | 34.6 | 52.4 | 46.0 | 27.1 |
| 39.2 | 42.9 | 38.3 | 40.5 | 33.7 | 38.3 | 40.9 | 39.7 | 42.4 | 66.5 | 44.6 | 39.3 | 45.8 | 30.2 | 30.6 | 37.4 | |
| 31.3 | 26.0 | 31.1 | 26.3 | 34.2 | 15.7 | 19.5 | 23.4 | 22.1 | 16.3 | 31.1 | 24.2 | 19.6 | 17.3 | 23.4 | 35.5 | |
| 6 | 21.5 | 22.5 | 29.7 | 32.3 | 35.2 | 34.1 | 31.9 | 33.8 | 29.4 | 27.6 | 17.7 | 18.4 | 33.7 | 52.9 | 51.6 | 27.7 |
| 45.3 | 45.2 | 39.4 | 33.4 | 38.5 | 31.3 | 28.0 | 27.7 | 29.8 | 43.8 | 43.0 | 44.5 | 26.0 | 24.5 | 27.4 | 30.0 | |
| 33.2 | 32.3 | 30.9 | 34.3 | 26.3 | 34.6 | 40.1 | 38.5 | 40.8 | 28.6 | 39.3 | 37.1 | 40.3 | 22.6 | 21.0 | 42.3 | |
| 7 | 27.7 | 29.3 | 27.0 | 17.2 | 29.4 | 14.3 | 33.9 | 33.2 | 20.6 | 25.1 | 13.3 | 16,6 | 18.9 | 46.7 | 50.9 | 22.2 |
| 53.8 | 44.7 | 45.6 | 46.7 | 46.3 | 44.1 | 43.8 | 46.3 | 42.4 | 45.1 | 40.3 | 44.2 | 46.9 | 34.2 | 35.5 | 43.7 | |
| 18.5 | 27.0 | 27.4 | 36.1 | 24,3 | 41.6 | 22.3 | 20.5 | 37.0 | 29.8 | 46.4 | 39.2 | 34.2 | 19.1 | 13.6 | 35.1 |