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. 2021 May 20;2021(5):CD013600. doi: 10.1002/14651858.CD013600.pub4

Comparison 4. Subgroup analysis: duration since symptom onset for the comparison of convalescent plasma versus placebo or standard care alone for individuals with moderate to severe disease.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
4.1 All‐cause mortality at up to day 28 1 11552 Risk Ratio (M‐H, Random, 95% CI) 0.98 [0.88, 1.10]
4.1.1 Duration of symptom onset up to 7 days 1 4466 Risk Ratio (M‐H, Random, 95% CI) 0.93 [0.84, 1.02]
4.1.2 Duration of symptom onset more than 7 days 1 7086 Risk Ratio (M‐H, Random, 95% CI) 1.04 [0.95, 1.14]