| O’Donnell 2021 |
Low risk of bias |
Participants were block randomized using a web‐based randomization platform in a 2:1 ratio to receive either convalescent plasma or standard plasma and the allocation sequence was concealed. There are no baseline differences that would suggest a problem with randomisation. |
Low risk of bias |
Both participants and people delivering the intervention were unaware of the assigned intervention received and the analysis was appropriate. |
Low risk of bias |
Data for this outcome was available for nearly all (219 out of 223) participants randomized. |
Low risk of bias |
The measurement of the outcome was appropriate and it is unlikely that it differed between intervention groups. The outcome assessors were unaware of the intervention received. |
Low risk of bias |
The data that produced this result was analysed in accordance with the predefined outcomes stated in the trial registration. |
Low risk of bias |
For the outcome "serious adverse events", there is a low risk of bias for all the domains. |
