| Study characteristics |
| Methods |
RCT; 2 groups |
| Participants |
24 multiple myeloma patients receiving high‐dose chemotherapy and tandem peripheral blood stem cell transplantation |
| Interventions |
Exercise: individualised home‐based programme of strength and aerobic training
Control: no individual programme, advised to remain active and walk for 20 mins at least 3 times/week |
| Outcomes |
Fatigue
Mood disturbance
Sleep variables
Body composition
Strength
Aerobic capacity |
| Notes |
Methodological quality score: 2
Main purpose of exercise: to improve fatigue and sleep |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Unclear risk |
"randomly assigned" but method of sequence generation not described |
| Allocation concealment (selection bias) |
Unclear risk |
"having a research assistant draw a sealed envelope containing group assignment", envelope not described as 'opaque' |
| Blinding of outcome assessment (detection bias)
All outcomes |
High risk |
Blinding not done |
| Incomplete outcome data (attrition bias)
All outcomes |
Unclear risk |
Not all participants accounted for and not clear whether intention‐to‐treat analysis was undertaken |
| Selective reporting (reporting bias) |
Low risk |
Fatigue outcome reported |
