Liu 1999.
| Study characteristics | ||
| Methods | RCT design: parallel‐group trial Total N randomised: unclear Length of follow‐up: 4 weeks Analysis: unclear |
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| Participants | Location: China Number of study centres and setting: patients from 1 hospital CAD diagnosis: MI as confirmed by electrocardiography Depression diagnosis: Center for Epidemiologic Studies ‐ Depression Scale (CES‐D), HAM‐D, diagnosis according to Chinese Classification of Mental Disorders, Second Edition, Revised (CCMD‐2‐R) Other entry criteria: unclear Exclusion criteria: unclear Treatment N: 31 (32% female, mean age unclear) Control N: 37 (27% female, mean age unclear) Comparability of groups: no significant differences |
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| Interventions | Treatment: fluoxetine Control: placebo Duration of treatment: 4 weeks |
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| Outcomes | Review outcomes: depression symptoms (HAM‐D), depression response, all‐cause mortality, cardiac events Other outcomes: heart rate variability |
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| Funding | Unclear | |
| Notes | Comment: translated paper | |
| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Random sequence generation (selection bias) | Unclear risk | Comment: No sufficient information provided |
| Allocation concealment (selection bias) | Unclear risk | Comment: No sufficient information provided |
| Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | Comment: No sufficient information provided Quote: "double‐blind controlled trial" (pg. 210) |
| Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Comment: No sufficient information provided |
| Incomplete outcome data (attrition bias) All outcomes | Unclear risk | Comment: No sufficient information provided |
| Selective reporting (reporting bias) | Unclear risk | Comment: No sufficient information provided |
| Other bias | Unclear risk | Comment: translated paper |