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. 2022 Jan 11;43(8):1889–1904. doi: 10.1038/s41401-021-00838-7

Fig. 5.

Fig. 5

Outline of the malate aspartate shuttle. ASPAR, aspartate; AST, aspartate aminotransferase; α-KGLUT, α-ketoglutarate; GLUT, glutamate; MDH, malate dehydrogenase; OAA, oxaloacetate. The net shuttle result is a transfer of the cytosolic NADH to the mitochondrial matrix.