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. 2022 Oct 17;12(10):1727. doi: 10.3390/jpm12101727

Table 9.

Metabolites and their pathways which correlate with aberrant behavior.

Significant Metabolites Significant Pathways
Metabolite r Pathway Matched Metabolites Impact
L-3-Phenyllactic acid *** −0.39 Phenylalanine metabolism ** Phenylpyruvate **,
2-Hydroxyphenylacetate *
0.26
Phenylpyruvic acid ** −0.35
D-Leucic acid ** −0.34 Phenylalanine, tyrosine and tryptophan biosynthesis * Phenylpyruvate ** 0
Guanine * −0.26
3-Hexenedioic acid * −0.25
L-Arabinose * 0.25
Ortho-Hydroxyphenylacetic acid * −0.25
Amiloride * 0.24
Glucuronic acid * −0.24
3S-methyl-2-oxo-pentanoic acid * −0.23
Cytidine * 0.23
L-Alpha-aminobutyric acid * −0.23
3-Hydroxyisovaleric acid * −0.22
Caprylic acid * −0.22

* p ≤ 0.05, ** p ≤ 0.01; *** p ≤ 0.001.