. 2022 Oct 17;12(10):1727. doi: 10.3390/jpm12101727

Table 17.

Metabolites and their pathways which correlate with proton-leak respiration.

Significant Metabolites		Significant Pathways
Metabolite	r	Pathway	Matched Metabolites	Impact
L-Proline **	0.28	Aminoacyl-tRNA biosynthesis ***	L-Histidine , L-Glutamine , L-Proline **	0
Acetamide *	0.26	Aminoacyl-tRNA biosynthesis ***	L-Histidine , L-Glutamine , L-Proline **	0
3-Hydroxyisovaleric acid *	0.26	D-Glutamine and D-glutamate metabolism *	L-Glutamine *	0
L-Glutamine *	0.25	D-Glutamine and D-glutamate metabolism *	L-Glutamine *	0
Ribitol *	0.22	Nitrogen metabolism *	L-Glutamine *	0
L-Histidine *	0.21
DL-Acetylcarnitine *	0.21

* p ≤ 0.05, ** p ≤ 0.01; *** p ≤ 0.001.