Figure 2.
Group Means of Gamma Activity. Un-medicated adults with ADHD exhibited significantly less gamma activity relative to their healthy peers during the standard 200-500 ms time window (grey), and during an earlier window from 50-200 ms post-stimulus (black). On the y-axis, gamma activity is shown in normalized units relative to a −200 to 0 ms pre-stimulus period. The administration of amphetamine (MAS-XR) significantly increased gamma activity in participants with ADHD during both time windows, and the magnitude of this increase eliminated group statistical differences in Run 2. Control subjects showed no significant effects from Run 1 to Run 2. These data indicate that stimulant medications may modulate cortical gamma activation in adults with ADHD. Error bars indicate one standard error of the mean.