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. 2022 Dec 13;8(12):e12193. doi: 10.1016/j.heliyon.2022.e12193

Table 2.

Modified composites for cardiac tissue engineering.

Scaffold type Cell type Results Reference
PU-GNT/NW composite scaffolds H9C2 rat cardiomyocytes More native morphology, increased proliferation and increased expression level of genes related to cardiac differentiation (Ganji et al., 2016)
AuNPS–Cs thermosensitive hydrogels MSCs Survival and metabolism of mesenchymal stem cells, differentiation into cardiac lineage (Baei et al., 2016)
Fullerenol/alginate hydrogel BADSCs Reducing the amount of oxidative stress, increasing the amount of angiogenesis and improving heart function (Hao et al., 2017)
PCL/PEG/MWCNTs with FG-coating nanocomposite scaffolds Mouse myoblasts Increase in electrical conductivity, increase in wettability, distribution and proper development of myoblasts (Mehdikhani and Ghaziof 2018)
GelMA-AuNWs hybrid hydrogels Neonatal rat cardiomyocytes Better biological activity, synchronous activity and faster spontaneous rate of cardiomyocytes (Li et al., 2020)
PCL/Gt/CNT ECS cells Increasing biocompatibility, increasing the length of cells and an excellent candidate for making vessels (Jiang et al., 2021)

Graphene oxide: GO; Carbon nanotubes: CNT, Gold nanoparticles: AuNPs; Gelatin: Gt; polycaprolactone: PCL; polyethylene glycol: PEG; Chitosan: CS; mesenchymal stem cells: MSCs; Polyurethane: PU; Gold nanotube: GNT; MWCNTs: multi wall carbon nanotubes; Brown adipose-derived stem cells: BADSCs.