Table 3.
Carbon based nanomaterials for nerve regeneration.
| Scaffold type | Application | References |
|---|---|---|
| Conductive nanofibrous CNT/poly (L-Lactic acid) composite scaffold | Scaffold to support olfactory ensheathing glial cell (OEC) adhesion, growth, survival, and proliferation | (Kabiri et al., 2015) |
| Poly-lactide-co-glycolide/carbon nanotube nanofibrous scaffolds by laminin protein | Scaffold to induce proliferation of neural cells and extensive neuronal growth | (Nazeri et al., 2021) |
| PPDO + CNTs nanofibers | Scaffold to accelerate mesenchymal stem cells differentiation and maturation into Schwann cell-like cells | (Wu et al., 2022) |
| Polyurethane/silk-functionalized MWCNTs | To induce neuroregeneration | (Shrestha et al., 2019) |
| Cs/PEG/MWCNTs composite scaffolds | Scaffold to increase cellular adhesion, growth, proliferation and neuronal differentiation | (Sang et al., 2022) |
| CNT incorporated in polycaprolactone fumarate (PCLF) | Scaffold to increase PC-12 cell proliferation, migration and neurite extension | (Zhou et al., 2018) |
| In situ hydrogel-forming scaffold loaded by PLGA microspheres containing carbon nanotube | Scaffold to stimulate adhesion, proliferation and differentiation of neural stem cells (NSCs) derived from MSC | (Shafiee et al., 2021) |
| Chitin/carbon nanotubes composite hydrogel | Scaffold to enhance hemo-compatibility, cell viability, proliferation and neurite outgrowth | (Wu et al., 2017) |
| PEG and CNTs hydrogel | Scaffold to facilitate Neuronal Differentiation | (Ye et al., 2021) |
| Embedded graphene and CNTs into poly(caprolactone fumarate) (PCLF)+MTAC | Scaffold to improve nerve cells differentiation | (Sun et al., 2021) |
| Poly(lactic-co-glycolic acid) (PLGA)/CNTs | Scaffold for BV2 and RGCs cells growth and differentiation of human induced pluripotent stem cells (hiPSCs) into retinal ganglion Cell (RGC) | (Yang et al., 2021) |
| PLDLA + CNT + PGFs | Scaffold for regeneration of transected sciatic nerve | (Ahn et al., 2015) |
| Nerve conduit based on CNT and Sericin | Scaffold for peripheral nerve injury | (Li et al., 2020) |
| Gelatin methacrylamide hydrogel with graphene nanoplatelets | differentiation and elongation neurite of stem cells into neural cells for nerve tissue engineering | (Wei et al., 2016) |
| Incorporated rGO into PEDOT microfibers | Scaffold to Enhance Neural Differentiation of Mesenchymal Stem Cells | (Guo et al., 2016) |
| Smart electrospun nanofibers containing PCL/Gt/GO | Scaffold to improve Antibacterial properties, sustainable release of drug, hydrophilicity and conductivity intended nerve tissue engineering | (Heidari et al., 2019) |
| Poly (trimethylene carbonate)/reduced graphene oxide-graft-poly (trimethylene carbonate) | Scaffold to enhance cell viability for nerve regeneration | (Guo et al., 2019) |
| rGO-GelMA-PCL hybrid nanofibers | Scaffold to improve electrical conductivity, biocompatibility, proliferation, differentiation and sensory/motor function recovery of injured rats | (Fang et al., 2020) |
| GO and electroactive reduced graphene oxide | Scaffold for cells proliferation and metabolic activity intended peripheral nerve injury regeneration | (Magaz et al., 2021) |
| Raffinose-grafted GO in silk fibroin-based scaffold | Scaffold to enhance viability, proliferation and differentiation of neural progenitor cells | (Jafari et al., 2021) |