TABLE 17.
Molecular chaperones and chaperonins in the three phylogenetic domains
| Protein in bacteriaa | Equivalent protein in:
|
|
|---|---|---|
| Archaeaa | Eucaryaa | |
| GroEL (Hsp60) | Nob | mt, chl: Hsp60 (Rubisco subunit binding protein); ct, ER: No |
| GroES (Hsp10) | No | mt, chl: Yes; ct, ER: No |
| No | TF55; thermosome subunits | ct: TRiC (CCT; TCP-1) subunits; mt, chl, ER: No |
| G+, DnaK(Hsp70) | Hsp70(DnaK)c; No-hyp. | No |
| G−, DnaK(Hsp70) | No | mt, chl: Hsp70; ct, ER: Hsp70 para.f |
| DnaJ(Hsp40) | Hsp40(DnaJ)c; No-hyp. | ct, mt, chl, ER: Yes |
| GrpE | GrpE; No-hyp. | mt, chl: Yes; ct, ER: No |
| G−, HptG | No | ct, ER: Hsp90 para.; mt, chl: No |
a
Abbreviations: mt, mitochondria; chl, chloroplast; ct, cytosol; ER, endoplasmic reticulum; G+ and G−, gram-positive and -negative type of DnaK, respectively. No-hyp., not yet investigated, or investigated but not yet found in hyperthermophiles; para., paralogous.
b
No, not yet investigated or not well characterized, or investigated but not yet found.
c
Protein similar to homologs in gram-positive bacteria but transcription initiation mechanism similar to that of eucarya.